Abstract

Effects on the duration of pseudopregnancy (PSP) of prolactin, LH, FSH, or various combinations of those hormones were studied in female rats. Hormones were implanted in the ovarian bursae on day 4, 7, or 9 of PSP or consecutively on days 4, 5, and 6. Prolactin, in doses ranging from 3 to 642 μg, and LH or FSH, at 3 μg, had no effect on PSP. However, 17 μg or more of LH implanted on day 4 or 7 significantly (p 80 μg) likewise prolonged PSP, but lower doses (17 or 56 μg) implanted on day 7 were less effective. The effect of consecutive (days 4-6) implantation of LH or FSH was similar to that of a single (day 4) LH or FSH implant. There was no synergism among prolactin, LH, and⁄or FSH when equal amounts of those hormones were implanted simultaneously on day 7 or 9. Neither LH nor FSH, when implanted on day 9, affected PSP. Ova were not found in 15 rats 24 hr after implantation on day 7 of 17 μg or 68 μg of LH or 17 μg of FSH, suggest...

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