Abstract
Mouse EL-4 T-lymphoma cells and B16 melanoma cells were incubated in a static magnetic field at 6.34 tesla (T) in NMR sample tubes for various time intervals at 37°C. After being exposed to the magnetic field, the tumor cells were tested for proliferative and metastatic activities. The exposed EL-4 cells and B16 cells proliferated more rapidly than the sham-exposed corresponding control tumor cells. Intravenous injection of the exposed B16 cells into C57BL/6- beige/ beige mice, produced a significantly larger number of pulmonary metastatic nodules than injection of the sham-exposed B16 cells. These findings suggest that strong static magnetic fields augment the cell proliferative activity and may promote the metastasis of tumor cells under certain conditions.
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