Abstract
Prolan, a hormone of the anterior pituitary gland, was discovered in the hypophysis by Evans, Smiths and Tsondek, in urine it was discovered by B. Tsondek and Ashheim in 1927. There is a certain close relationship between the genital glands and the anterior pituitary gland. It has long been known that a number of macroscopic and microscopic changes are observed in the pituitary gland during pregnancy and castration. The works of Biedl, Aschner, Ashheim, Tsondek, Steinach and others indicate that Prolan affects the maturation and rejuvenation of the body.
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