Projet REUSE: utilisation du dossier patient informatisé (DPI) en recherche clinique

Abstract

Integrating clinical research data entry with patient care data entry is a challenging issue. At the G. Pompidou European Hospital (HEGP), pulmonary function testing reports are captured twice, first in the Electronic Health Record (EHR) and then in Clinical Data Management System (CDMS). Statuary requirements and data standards are different for EHR and clinical research. So, this work has for object to suggest an integration solution between EHR and CDMS. This object can be divided in two steps: the first consists in modeling clinical research workflow in a university hospital environment in order to investigate the possible use of her in this context. The second step consist in conceiving, implementing and assessing an integration solution between EHR and CDMS taking into consideration standardization efforts and statuary requirements. The REUSE demonstrator showed that automatic transfer of data reduces errors risk, and enables to preserve collected data during clinical trials in the EHR that may be useful. We proposed the integration profile “Retrieve and Integrate Form for Data Capture”. Beyond syntactic interoperability, a perspective is to implement this integration profile in the REUSE demonstrator in order to address the issue of semantic interoperability between both domains.KeywordsHL7CDACDISCODMIHE profileRFDElectronic Health RecordClinical Data Management SystemBiomedical ResearchClinical trialPulmonary function testing