Progressive optic neuropathy secondary to JAK2 mutation-positive myeloproliferative neoplasm

Abstract

<br>We describe a 25-year-old male presenting with chronic papilledema due to cerebral venous sinus thrombosis (CVST) and was found to have a myeloproliferative disorder with JAK2 mutation. All measures to salvage vision were unfruitful from transverse sinus stenting, thecoperitoneal shunt to optic nerve sheath fenestration. This case illustrates the importance of screening for JAK2 mutation in patients with CVST and abnormal blood counts.<br>