Abstract
In 1958, Åström et al<sup>1</sup>described three cases of a clinically progressive, asymmetric disorder of the central nervous system (CNS) which they named "progressive multifocal leukoencephalopathy" (PML). This disorder was associated with Hodgkin's disease and chronic lymphocytic leukemia in their patients. In reviewing the literature at that time, they found five additional cases which fulfilled their criteria for PML.<sup>2-5</sup> Since 1958, many additional cases of PML associated with a variety of underlying disease processes have been described.<sup>6-56</sup>The purpose of the present report is to describe a new case of PML occurring in a patient with macroglobulinemia, an association not previously reported. Clinical, pathological, and virologic findings are described. <h3>Patient Summary</h3> A 61-year-old white man was first seen in a local hospital in December 1958 complaining of shortness of breath and abdominal distension. Physical examination revealed a right upper quadrant abdominal mass and a right pleural
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
