Abstract
A 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histopathologic findings, we diagnosed progressive macular hypomelanosis (PMH). It is a nonscaly disorder with hypopigmented macules mainly on the trunk and is more often seen in young women. In contrast to some authors assuming the presence of Propionibacterium spp. as a matter of principle in PMH, we report a case with no evidence for Propionibacterium spp.
Highlights
Hypopigmented lesions of the skin are common and display in general no diagnostic challenge
In Caucasians, in particular in persons with light skin type I to III according to Fitzpatrick [1], progressive macular hypomelanosis (PMH) is a rarely diagnosed disease posing a relevant differential diagnosis for hypopigmentations
We here report on a female Caucasian patient with PMH living in Germany who observed an increase in hypopigmentation after pregnancies
Summary
Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians.
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