Progression of visual field in patients with primary open‐angle glaucoma (1): Preliminary results

Abstract

AbstractPurpose To evaluate the visual field rate of progression of patients with treated ocular hypertension (OHT) and primary‐open angle glaucoma (POAG).Methods From a multicentric database, 441 eyes of 228 patients with treated ocular hypertension or POAG followed up at least 6 years with Humphrey 24.2 Sita‐Standard visual field examination at least twice a year were identified. From initial data, eyes were classified in 5 groups: 104 ocular hypertension, 205 early glaucoma (MD>‐6dB), 45 moderate glaucoma (MD ‐6 to ‐12dB), 41 advanced glaucoma (MD ‐12 to ‐18dB) and 46 severe glaucoma (MD<‐18dB). Rate of progression during the follow‐up period was calculated using the trend analysis of the Guided Progression Analysis software.Results The mean duration of follow‐up was 8.4 years. We found a significant positive association between initial MD and rate of progression in early, moderate and advanced glaucoma (p<0.04). Rate of progression was ‐0.06 dB/year (‐0.19 %VFI/year) in eyes with ocular hypertension, ‐0.24 dB/year (‐0.75 %VFI/year) in eyes with early glaucoma, ‐0.45 dB/year (‐1.72 %VFI/year) in moderate glaucoma, ‐0.54 dB/year (‐2.44 %VFI/year) in advanced glaucoma, and ‐0.45 dB/year (‐1.97 %VFI/year) in severe glaucoma.Conclusion In early to advanced stages of glaucoma, the rate of progression worsened as the severity increased, but became smaller in latest stage of the disease.