Abstract
We describe a unique case of bilateral acquired vitelliform lesions in a 67-year-old-female with pachychoroid associated with subretinal fluid in the right eye (OD) and a nonexudative choroidal neovascular membrane (CNVM) in the left eye (OS). Multimodal imaging performed at baseline and over the ensuing two years showed an increase in the OS vitelliform lesions with a concurrent transformation of quiescent CNVM to an exudative form. Further studies are warranted to gain better insight into the etiopathogenesis of these vitelliform lesions in pachychoroid and their potential role in instigating CNVM activation.
Highlights
Acquired vitelliform lesions (AVL) are a focal or multifocal subretinal accumulation of autofluorescent material reported in various dystrophic, degenerative, paraneoplastic, toxic, and vitreoretinal interface disorders involving the macula [1]
The natural course of these lesions is often a gradual decrease in size with fragmentation and slow resorption, resulting in photoreceptor disruption and eventual atrophy [2]. We demonstrate that these acquired vitelliform deposits herald the transformation of a nonexudative choroidal neovascular membrane (CNVM) to an exudative one in a patient with pachychoroid
The purpose of this case report was to highlight the conversion of quiescent pachychoroid neovasculopathy (PNV) to an exudative network with progressive deposition of AVL
Summary
Acquired vitelliform lesions (AVL) are a focal or multifocal subretinal accumulation of autofluorescent material reported in various dystrophic, degenerative, paraneoplastic, toxic, and vitreoretinal interface disorders involving the macula [1]. The natural course of these lesions is often a gradual decrease in size with fragmentation and slow resorption, resulting in photoreceptor disruption and eventual atrophy [2]. In this case report, we demonstrate that these acquired vitelliform deposits herald the transformation of a nonexudative choroidal neovascular membrane (CNVM) to an exudative one in a patient with pachychoroid
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