Abstract
Secreted frizzled-related protein (SFRP) can inhibit the expression of Wnt signaling pathway through Frizzled protein. The silencing of SFRP gene promoter methylation is associated with the occurrence and metastasis of many cancers such as colorectal cancer, gastric cancer, liver carcinoma, lung cancer and ovarian cancer. Several studies have found that SFRP gene has latent clinical value, which is expected to become the novel target for the gene diagnosis and treatment of cancer. Key words: Signal transduction; Targeted gene repair; Neoplasms; Secreted frizzled-related protein
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.