Abstract

The patient is a 22-year-old female with recurrent respiratory papillomatosis (RRP) requiring multiple laser ablations, presents for fiberoptic bronchoscopy due to worsening cavitary lesions of the right upper lobe seen on computed tomography (CT) scans. While these lesions were first attributed to her human papillomavirus (HPV) infection, bronchial cultures revealed a methicillin-sensitive Staphylococcus aureus (MSSA) infection. Not only is this case a unique presentation of concurrent RRP and MSSA cavitary lesions, it also highlights the importance of avoiding anchoring bias and initiating investigations for other differential diagnoses. We will review epidemiology, pathogenesis, and current therapeutics of RRP.

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