Abstract
Raltitrexed is a kind of specific thymidylate synthase inhibitor, and as a novel cytotoxic drug, it is used in the treatment of a variety of solid tumors, with the advantages of good effect, light adverse reaction and easy to use.Especially in the treatment of the colorectal cancer, its efficacy has been recognized.And in clinical, raltitrexed can plug with chemotherapy or targeted drug combination, as well as radiosensitizer.This review summarized the raltitrexed research progress on the treatment of colorectal cancer in recent years. Key words: Raltitrexed; 5-Fluorouracil; Tymidylate synthase; Colorectal cancer; Radiotherapy
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