Abstract
Normal-pressure hydrocephalus is a clinical syndrome that mainly targets the elderly population. It features dementia, impaired walking, and the malfunction of sphincters. The rapid identification and large-scale screening of patients with normal-pressure hydrocephalus (NPH) are of great significance as surgical interventions can greatly improve or even reverse the symptoms. This review aims to summarize the traditional parameters used to diagnose NPH and the emerging progression in neuroimaging of the disease, hoping to provide an up-to-date overall perspective and summarize the possible direction of its future development.
Highlights
Normal-pressure hydrocephalus is a concept first raised by Hakim and Adams in 1965, who defined the disease with two elementary ideas—symptomatic ventriculomegaly and cerebrospinal fluid (CSF) pressure within a normal range (
In addition to invasive measures like tap test, non-invasive imaging examination are of great value
Multiple radiological markers are summarized in this review
Summary
Reviewed by: Alessia Sarica, University of Magna Graecia, Italy Ville Leinonen, Kuopio University Hospital, Finland. Specialty section: This article was submitted to Applied Neuroimaging, a section of the journal Frontiers in Neurology. Normal-pressure hydrocephalus is a clinical syndrome that mainly targets the elderly population. It features dementia, impaired walking, and the malfunction of sphincters. The rapid identification and large-scale screening of patients with normal-pressure hydrocephalus (NPH) are of great significance as surgical interventions can greatly improve or even reverse the symptoms. This review aims to summarize the traditional parameters used to diagnose NPH and the emerging progression in neuroimaging of the disease, hoping to provide an up-to-date overall perspective and summarize the possible direction of its future development
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