Abstract

Influenza is a highly known contagious viral infection that has been responsible for the death of many people in history with pandemics. These pandemics have been occurring every 10 to 30 years in the last century. The most recent global pandemic prior to COVID-19 was the 2009 influenza A (H1N1) pandemic. A decade ago, the H1N1 virus caused 12,500 deaths in just 19 months globally. Now, again, the world has been challenged with another pandemic. Since December 2019, the first case of a novel coronavirus (COVID-19) infection was detected in Wuhan. This infection has risen rapidly throughout the world; even the World Health Organization (WHO) announced COVID-19 as a worldwide emergency to ensure human health and public safety. This review article aims to discuss important issues relating to COVID-19, including clinical, epidemiological, and pathological features of COVID-19 and recent progress in diagnosis and treatment approaches for the COVID-19 infection. We also highlight key similarities and differences between COVID-19 and influenza A to ensure the theoretical and practical details of COVID-19.

Highlights

  • Aziz et al investigated the role of GI symptoms in predicting the severity of COVID-19. They indicated that GI symptoms, especially diarrhea, is associated with worse outcome [91]. All these findings suggest that COVID-19 is actively involved in GI tract infection

  • A prospective study with 10 severe COVID-19 patients was performed by Kai Duan et al in China, in which transfusion of high neutralizing antibody titers CP was applied in seriously ill patients to improve antiviral activity

  • This review study was conducted to increase our understanding of both COVID-19 and influenza A (H1N1)

Read more

Summary

Introduction

Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. According to a recent World Health Organization survey, the COVID-19 attack and disease burden in children have been much lower than influenza outbreaks, and the secondary household attack rate has been low This is in stark contrast to reports of the virus spreading quickly in enclosed spaces like hospitals or cruise ships, as well as a high prevalence of healthcare-associated infections [12]. This narrative analysis report aims to summarize and compare early studies on the epidemiology, clinical effects, diagnosis, treatment, and prevention of COVID-19 and influenza A to provide theoretical and practical details

Virology and Structural Characteristics
Influenza
Epidemiological Prospective of COVID-19
Death Rate by Age Group
Death Rate by Gender Ratio
Death Rate by Health Conditions
Death Rate by Sex Ratio
Transmission
Replication
Clinical Manifestation of COVID-19
Cardiovascular
Why Women Have Less Tendency to Be Affected by Viral Infections?
Diagnosis of COVID-19
Molecular Tests
Lymphopenia
Gut Microbiome
Conventional Culture
Antigen Detection
Availability of Treatment against COVID-19
Prevention and Control of COVID-19
Prevention and Control of Influenzaemulsion
COVID-19
Inactive and Live-Attenuated Vaccines
Designing Nucleic Acid-Based Vaccines
Viral Vectors
Protein Vaccines
10.1.1. Egg-Based Vaccines
10.1.2. Attenuated Vaccines
10.1.3. Recombinant Vaccines
Findings
11. Conclusions
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call