Abstract
Managing hypertension after acute stroke has been a longstanding, and still ongoing, controversy. On the one hand, clinical studies are near consistent in showing positive relations between increasing blood pressure (BP) and adverse outcomes in both acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH), which supports pathophysiological mechanisms of hypertension-induced endothelial stress and blood-brain barrier disruption.1 Conversely, randomized controlled trials of BP lowering have shown variable results in mixed and pathologically distinct stroke subtypes,2-4 which has fuelled debate over the potential for adverse effects of such treatment when cerebral autoregulation and collateral blood flow are disrupted by ischemia.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.