Abstract

Rubella is the leading vaccine-preventable cause of birth defects. Rubella typically manifests as a mild febrile rash illness; however, infection during pregnancy, particularly during the first trimester, can result in miscarriage, fetal death, or a constellation of malformations known as congenital rubella syndrome (CRS), commonly including one or more visual, auditory, or cardiac defects (1). In 2012, the Regional Committee of the World Health Organization (WHO) Western Pacific Region (WPR)* committed to accelerate rubella control, and in 2017, resolved that all countries or areas (countries) in WPR should aim for rubella elimination† as soon as possible (2,3). WPR countries are capitalizing on measles elimination activities, using a combined measles and rubella vaccine, case-based surveillance for febrile rash illness, and integrated diagnostic testing for measles and rubella. This report summarizes progress toward rubella elimination and CRS prevention in WPR during 2000-2019. Coverage with a first dose of rubella-containing vaccine (RCV1) increased from 11% in 2000 to 96% in 2019. During 1970-2019, approximately 84 million persons were vaccinated through 62 supplementary immunization activities (SIAs) conducted in 27 countries. Reported rubella incidence increased from 35.5 to 71.3 cases per million population among reporting countries during 2000-2008, decreased to 2.1 in 2017, and then increased to 18.4 in 2019 as a result of outbreaks in China and Japan. Strong sustainable immunization programs, closing of existing immunity gaps, and maintenance of high-quality surveillance to respond rapidly to and contain outbreaks are needed in every WPR country to achieve rubella elimination in the region.

Highlights

  • A few countries (Japan, Solomon Islands, and Vietnam) identified CRS cases that occurred after outbreaks

  • Genotype 1J was detected in four Western Pacific Region (WPR) countries before 2013, but not since

  • The Pacific Islands Countries and Territories are reviewed as a single epidemiologic unit; they include American Samoa (United States), Cook Islands, Fiji, French Polynesia (France), Guam (United States), Kiribati, Marshall Islands, Micronesia, Nauru, New Caledonia (France), Niue (New Zealand), Northern Mariana Islands (United States), Palau, Samoa, Solomon Islands, Tokelau (New Zealand), Tonga, Tuvalu, Vanuatu, and Wallis and Futuna (France)

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Summary

Morbidity and Mortality Weekly Report

Mariano; Roberta Pastore, MD2; Varja Grabovac; Yoshihiro Takashima, MD, PhD2; James P. Rubella is the leading vaccine-preventable cause of birth defects. WPR countries are capitalizing on measles elimination activities, using a combined measles and rubella vaccine, case-based surveillance for febrile rash illness, and integrated diagnostic testing for measles and rubella. This report summarizes progress toward rubella elimination and CRS prevention in WPR during 2000–2019. Reported rubella incidence increased from 35.5 to 71.3 cases per million population among reporting countries during 2000–2008, decreased to 2.1 in 2017, and increased to 18.4 in 2019 as a result of outbreaks in China and Japan. Strong sustainable immunization programs, closing of existing immunity gaps, and maintenance of high-quality surveillance to respond rapidly to and contain outbreaks are needed in every WPR country to achieve rubella elimination in the region

Immunization Activities
Solomon Islands
Total Western Pacific Region****
Surveillance Activities
What is added by this report?
What are the implications for public health practice?
MMR MR
Findings
Discussion
Total Western Pacific Region
Full Text
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