Abstract

In 2010, all 53 countries* in the World Health Organization (WHO) European Region (EUR) reconfirmed their commitment to eliminating measles and rubella and congenital rubella syndrome (1); this goal was included as a priority in the European Vaccine Action Plan 2015-2020 (2). The WHO-recommended elimination strategies in EUR include 1) achieving and maintaining ≥95% coverage with 2 doses of measles-containing vaccine (MCV) through routine immunization services; 2) providing measles and rubella vaccination opportunities, including supplementary immunization activities (SIAs), to populations susceptible to measles or rubella; 3) strengthening surveillance by conducting case investigations and confirming suspected cases and outbreaks with laboratory results; and 4) improving the availability and use of evidence for the benefits and risks associated with vaccination (3). This report updates a previous report (4) and describes progress toward measles elimination in EUR during 2009-2018. During 2009-2017, estimated regional coverage with the first MCV dose (MCV1) was 93%-95%, and coverage with the second dose (MCV2) increased from 73% to 90%. In 2017, 30 (57%) countries achieved ≥95% MCV1 coverage, and 15 (28%) achieved ≥95% coverage with both doses. During 2009-2018, >16 million persons were vaccinated during SIAs in 13 (24%) countries. Measles incidence declined to 5.8 per 1 million population in 2016, but increased to 89.5 in 2018, because of large outbreaks in several EUR countries. To achieve measles elimination in EUR, measures are needed to strengthen immunization programs by ensuring ≥95% 2-dose MCV coverage in every district of each country, offering supplemental measles vaccination to susceptible adults, maintaining high-quality surveillance for rapid case detection and confirmation, and ensuring effective outbreak preparedness and response.

Highlights

  • World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) estimate vaccination coverage for all countries in the region using annual, government-reported administrative coverage data and vaccination coverage surveys (5)

  • ≥2 per 100,000 population); 2) the percentage of case investigations conducted within 48 hours of report; 3) the percentage of suspected cases with an adequate specimen collected within 28 days of rash onset and tested in a WHO-accredited or proficient laboratory; and 4) the percentage of cases for which the origin of infection is determined

  • During 2009–2018, the number of European Region (EUR) countries that met the target for suspected cases discarded as nonmeasles at the national level increased from one (3%) in 2009 to 10 (21%) in 2018 (Table 2)

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Summary

Morbidity and Mortality Weekly Report

MPH1; Mark Muscat, MD, PhD2; Simarjit Singh, MSc2; Myriam Ben Mamou MD2; Dragan Jankovic, MD2; Siddhartha Datta, MD2; James P. The. 1) achieving and maintaining ≥95% coverage with 2 doses of measles-containing vaccine (MCV) through routine immunization services; 2) providing measles and rubella vaccination opportunities, including supplementary immunization activities (SIAs), to populations susceptible to measles or rubella; 3) strengthening surveillance by conducting case investigations and confirming suspected cases and outbreaks with laboratory results; and 4) improving the availability and use of evidence for the benefits and risks associated with vaccination (3). To achieve measles elimination in EUR, measures are needed to strengthen immunization programs by ensuring ≥95% 2-dose MCV coverage in every district of each country, offering supplemental measles vaccination to susceptible adults, maintaining highquality surveillance for rapid case detection and confirmation, and ensuring effective outbreak preparedness and response

Immunization Activities
Surveillance Activities
Measles and Rubella Laboratory Network provides laboratory
Measles cases
Measles Incidence and Genotypes
Regional Verification of Measles Elimination
Discussion
European Region
The measles resurgence and the European Vaccine Action
CBS characteristic
Findings
What is added by this report?
What are the implications for public health practice?
Full Text
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