Abstract

is a globally distributed zoonotic disease, which can be expressed as multiple systems damage, among which Brucellar osteoarthritis is the common clinical manifestation. This review summarized the progress of treatment for Brucellar osteoarthritis. At present, the treatment of Brucellar osteoarthritis mainly include drug treatment and surgical treatment which were reported in domestic and foreign literatures. Drug treatment plan recommended by WHO is widely selected abroad and in our country we follow the Brucellosis Medical treatment program (trial edition) drug treatment program developed by Beijing Ditan Hospital, Capital Medical University in 2012, which mainly includes doxycycline, rifampicin, streptomycin, quinolones and cephalosporins. Early diagnosis and early, sufficient, adequate course of drug treatment for Brucellar osteoarthritis may achieve good curative effect. Surgical treatment should be applied for brucellar osteoarthritis patients with severe spinal and joint destruction. Key words: Brucella; Spondylitis; Osteoarthritis; Medical treatment; Surgical treatment

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