Progress on the non-coding RNA in brain metastasis of non-small cell lung cancer

Abstract

In recent years, more studies have shown that non-coding RNAs (ncRNAs) play an important role in the development of malignant tumors, in which microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play decisive roles. The expression of ncRNA in lung cancer, and its value in the diagnosis, prognosis and treatment of lung cancer have been reported in a large number of studies. Recently, the role of non-coding RNA in the development of brain metastases has also been identified. Non-small cell lung cancer (NSCLC) is the most common subtype of lung cancer, and brain metastasis is the most common cause of death in NSCLC. Currently, it is still difficult to diagnose and treat NSCLC brain metastases. This review summarizes the research progress of non-coding RNAs in NSCLC brain metastases. Key words: Non-small cell lung cancer; Brain metastasis; Non-coding RNA