Abstract

Bronchial asthma is a complex polygenic disease, caused by environmental and genetic factors.Three key methods are used to identify asthma susceptibility genes, including positional cloning study, candidate gene study and the emerging trend of genome-wide association study.Chain analysis and correlation analysis are two main strategies.This review discusses the asthma susceptibility genes: TLR, IL-13, PDCD4, CCL-5, TRPV1, BDNF in the perspective of functional classification. Key words: Asthma; Genetics; Susceptibility genes

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