Abstract
Multi-disciplinary therapy (MDT) based on the surgery is the fundamental treatment strategy for advanced gastric cancer. At present, the two main treatment modes are surgical-based adjuvant chemotherapy and neoadjuvant chemotherapy. In recent years, many clinical researches have shown that neoadjuvant chemotherapy can reach the descending stage and increase the R0 resection rate and reduce the local recurrence rate for patients with large tumors and deeper infiltration in Ⅲ stage and above. However, there is no consensus on the choice of neoadjuvant chemotherapy and the best course of treatment. In terms of safety, efficacy and evaluation mode, a complete consensus has not been reached; besides, the prediction of the efficacy of neoadjuvant therapy is not clear. This paper reviews the progress of neoadjuvant chemotherapy for gastric cancer. Key words: Stomach neoplasms; Surgical procedures, operative; Neoadjuvant therapy
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