Abstract

Cytomegalovirus is a DNA virus that has the potential to latent-reactivation in human body with immune deficiency.CMV infection is usually asymptoatic in an immunocompetent host, but it may attack immunocompromised population.IL-10 is an important immunoregulatory cytokine, it can attenuate and terminate viral response by multiple immunosuppressive ways: affecting the expression of pro-inflammatory cytokines and chemokines, regulating antigen presenting cells, and restraining effector cell and NK cell responses.Currently, many researchers report that IL-10 has close relationtship with immunologic mechanism of cytomegalovirus in host.This paper reviews the biological effect of IL-10 and effect of IL-10 in cytomegalovirus infection. Key words: Cytomegalovirus; IL-10

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