Abstract

Infective endocarditis(IE) is a kind of endocardial infection which cardiac intima is affected by some pathogens.Intravascular catheter, implantable artificial device and surgery are the common reasons for IE, congenital heart diseases and cardiac surgery are the main causes for IE in children.The incidence of infective endocarditis is high and case fatality rate is as high as 20%.The dominant pathogen of IE is gram-positive bacteria.Modified Duke standard is the gold standard in the diagnosis of IE, some other imaging evidence and new laboratory tests and biomarkers for diagnosis of IE have improved the sensitivity of the diagnostic criteria.Good oral hygiene and regular dental check are the most effective prevention measures.The idea of endocarditis management team in the newest guidelines on IE requires multidisciplinary experts to participate in diagnosis and treatment of IE.Individualized treatment is the best way to improve the patients survival rate. Key words: Infective endocarditis; Diagnosis; Treatment; Progress

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