Abstract
Maturity-onset diabetes of the young(MODY), a monogenic form of diabetes, has more than 8 well-known subtypes: MODY1(hepatocyte nuclear factor-4A, HNF4A), MODY2(glucokinase, GCK), MODY3(hepatocyte nuclear factor-1A, HNF1A), MODY4(pancreatic and duodenal homeobox, PDX), MODY5(hepatocyte nuclear factor-1B, HNF1B), MODY6(neuronal differentiation 1, NEUROD1), MODY7(carboxyl ester lipase, CEL) and MODY8(insulin, INS). The molecular pathology, clinical manifestations and treatment of MODYs are different and reviewed. Key words: Maturity-onset diabetes of the young; Adolescence; Gene; Pathology
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