Abstract
Glaucoma is characterized by progressive loss of retinal ganglion cell (RGCs), optic nerve atrophy, cupping of the optic disc, and specific visual field deficits. Elevated intraocular pressure (IOP) is considered to be a major risk factor associated with the development of this neuropathy, therefore, elevated IOP has been induced in animals to simulate key aspects of human glaucoma, in order to unlock the mechanism of this disease and seek out new therapeutic strategies. In the following review: (1) models used for the study of hypertensive glaucomatous neuropathy in rodents, (2) assessment of these animal models and (3) their usage will be described.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
