Progress of Cell‐Derived Biomimetic Drug Delivery Systems for Cancer Therapy

Abstract

AbstractCertain types of cells possess unique characteristics such as tumor homing and prolonged circulation in blood, which are worthy of being exploited in drug delivery carriers for cancer therapy. To improve the delivery efficiency, these cells are integrated with artificial nanocarriers and therapeutic agents to construct biomimetic drug delivery systems. This report provides an overview of recent advances in cell‐derived drug delivery systems for effective cancer treatment. The natural membranes of cells like red blood cells, cancer cells, leukocytes, stem cells, and so on, are extracted and used to form cell membrane–camouflaged nanocarriers, which take advantage of the outstanding biocompatibility and versatile functions of cell membranes. In addition, as an emerging field, biomimetic drug delivery platforms utilizing living cells are also introduced. Finally, the limitations of biomimetic drug delivery systems and the future outlook are discussed and proposed herein.