Abstract

The use of bone grafts to stimulate bone formation has been utilized treating spine disorders for centuries.The autograft remains the 'gold standard' because it remains the only graft material of three graft properties.Bone graft can be defined as structural or nonstructural.Half lamina excision and removal of nucleus pulposus limited nerve decompression surgery for the fusion, more extensive decompression fusion but maintain spinal structure is relatively intact, and fusion necessary spinal segment.There are some substituted algorithms for spine fusion.Despite significant advances in spinal instrumentation technology and surgical techniques, without solid bony fusion, all spinal instrumentation will eventually fail.Bone formation biology and recent innovations were evaluated in this article. Key words: Bone graft; Graft substitution; Intervertebral fusion, rhBMP-2, DBM TCP HA

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