Abstract

Autophagy plays an important role in the occurrence, progression and treatment of cancer, neurodegenerative, autoimmune and inflammatory diseases. Recent years, autophagy has become a new hot spot in tumor area. Chronic myelogenous leukemia (CML) is a common hematopoietic malignancy; while autophagy is involved in its development, as well as targeting drug tyrosine kinase inhibitor resistance mechanisms, regulating autophagy provide a new direction for the treatment of CML. The intensive study of the relation between cell autophagy and cancer will help to overcome cancer. This article offers an up-to-date comprehensive review of autophagy and CML. Key words: Leukemia, myelogenous, chronic; Autophagy

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