Progress of adverse pregnancy outcomes in polycystic ovary syndrome patients

Abstract

Polycystic ovary syndrome (PCOS) is a common disease that lead to endocrine disorders and infertility in women of child-bearing age. A large number of studies have shown that the pathogenesis of PCOS is related to insulin resistance (IR), hyperandrogenism and high body mass index. At present, remarkable progress has been made in the study of conception methods and the reduction of multiple pregnancies in PCOS patients. However, there is relatively little research on the adverse pregnancy outcomes after conception. Therefore, this study will use evidence-based medicine to make a review of complications in maternal. For instance, pregnancy-induced hypertension syndrome (PIH), gestational diabetes mellitus (GDM), miscarriage, premature delivery and so on. This study provides an overall basis for early prevention and intervention in clinical work through discussing the pathophysiology of PCOS, the risk factors of its occurrence and development, and the management strategies of pre-pregnancy and gestation period. Key words: Polycystic ovary syndrome; Pregnancy complications; Pregnancy outcome; Review