Abstract

Novel coronavirus disease (COVID-19) broke out in Wuhan, China, and has spread throughout the country, affecting many countries around the world. Because there is no etiological treatment for COVID-19, it is very urgent to find effective antiviral drugs to control the rapid spread of this disease. Remdesivir is a nucleotide prodrug that has broad-spectrum antiviral activity. It can interfere with viral RNA synthesis and play an antiviral role. This article reviews the pharmacological effects of remdesivir, some animal trials, in vitro and in vivo experiments, and clinical trials.

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