Abstract

The incidence of gestational diabetes mellitus (GDM) is increasing. GDM is associated with adverse pregnancy outcomes and has long-term implications for both mother and child. The management of GDM is still controversial. As insulin therapy is effective and safe, it is considered as the first choice of pharmacotherapy for GDM. Recent studies have shown that the short acting insulin analogs such as lispro and aspart, and oral anti-diabetic agents such as glyburide and metformin, are safe, but there are only limited data to support the use of long acting insulin analogs. Key words: Gestational diabetes mellitus; Insulin analogs; Oral anti-diabetic agents

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