Progress in the pathogenesis of bronchopulmonary dysplasia

Abstract

Bronchopulmonary dysplasia （ BPD） is a main cause of morbidity and mortality in preterm infant,so the etiology and pathogenesis of BPD is one of the hot issues in the neonatal medical research. Present studies,not only focus on the congenital factors,including genetic susceptibility and lung immaturity,but also the acquired factors,including oxygen toxicity,barotrauma and capacity of injury,infection or inflammation. This pa-per reviews recent research progress on the etiology and pathogenesis of new pulmonary hypoplasia. Key words: Bronchopulmonary dysplasia; Pathogenesis; Etiology