Progress in the application of ezetimibe combined with statins in cardiovascular and cerebrovascular diseases

Abstract

As one of the main risk factors of cardiovascular and cerebrovascular diseases, hyperlipidemia has a great impact on the quality of life of patients. Statins, as first-line lipid-lowering drugs, have been clinically proven, but for high-risk patients with cardiovascular and cerebrovascular diseases caused by hyperlipidemia, the optimal lipid-lowering effect cannot be achieved by increasing the basic dosage. Therefore, the therapeutic effect of the new drug Ezetimibe combined with statins is superior to that of single drug. In order to better cure this disease, a large number of relevant literatures at home and abroad were searched. The pharmacological mechanism of ezetimibe, the new way of combining with statins, the research status and advantages of cardiovascular and cerebrovascular diseases were expounded, which provided reference for the cure of cardiovascular and cerebrovascular diseases.