Progress in Synthesis of Glycidol

Abstract

The molecular structure of glycidol contains two highly active chemical functional groups, epoxy group and hydroxyl group, so it is very active and is a very useful chemical substance. It can be used as plastics, fiber modifiers, epoxy resin diluents, halogenated hydrocarbon stabilizers, food preservatives, fungicides, etc. In the pharmaceutical field, it can be used to synthesize a series of blockers for cardiovascular diseases, HIV protease inhibitor for AIDS, antiviral drug, many lactones and glycerophospholipid, it can also be used as an important intermediate of some photoelectric materials and functional polymer materials. The partial reactivity of glycidyl depends on its epoxy ring acting as an alkylating agent. In addition, it is used in the production of flavorings and sweeteners. Glycidyl can also be used as a stabilizer, used in the production of petroleum, vinyl polymers, demulsifiers, dyeing layered agents and gelata applied in surface coatings, chemical synthesis, fungicides, solid fuels. It's also an important monomer and semi-finished product for synthetic surfactant. And its derivatives are also a kind of chemical raw materials, which are used in many fields such as resins, plastics, medicines, pesticides and auxiliaries. Therefore, more and more attention are paid to the synthesis and application of glycidol. However, the application of glycerol in our country is limited, and the industrial production is also lagging behind. In this paper, the process of glycidol synthesis form propylene alcohol and glycerol as basic raw material was reviewed, and the preparation of glycidol was systematically summarized, so as to provide reference for the subsequent research of glycidol.