Progress in molecular diagnostic techniques for leukemia

Abstract

With the development of molecular diagnostic techniques, the study for the etiology of leukemia has been entering the era of the molecular biology. Molecular techniques for leukemia diagnosis, prognosis and individualized therapy are used widely, becoming one of the necessary routine tests for patients with leukemia. So far, molecular techniques for leukemiaincluding cytogenetic diagnosis, molecular genetics, molecular diagnostics based on PCR, mutation detection, as well as a variety of next–generation sequencing, have played an important role in the diagnosis of leukemia, minimal residual disease monitoring, prognosis and targeted therapy. (Chin J Lab Med, 2015, 38: 206–210) Key words: Leukemia; Molecular diagnostic techniques