Abstract
Vesicoureteral reflux, a most common congenital anomaly of the kidney and urinary tract, is associated with the malformation of ureterovesical junction.It does not cause any specific symptoms or signs unless it is part of a syndrome or complicated by urinary tract infection.The exact cause is not clear, and genes or environmental factors may result in vesicoureteral reflux.The prevalence of siblings and offspring of reflux patients are higher than normal control groups, so the genetic screening is necessary.This article will review the genetics of vesicoureteral reflux and possible interactions. Key words: Vesicoureteral reflux; Congenital anomalies of kidney and urinary tract; Gene; Ureteric bud; Metanephric mesenchyme
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