Abstract
Hemophagocytic syndrome (HS) is a syndrome characterized with complicated etiology and mechanism,the pathological hallmark of this syndrome is unregulated proliferation and activation of histio-cytes and phagocytosis. HS comprises the primary forms and secondary forms,the primary forms are related to the familial genetic defects,and the secondary forms are caused by acquired infections,especially the Epstein-Barr virus ( EBV) infection. EBV-associated HS is a rapidly progressive disease with a high rate of mortality. In this paper,we aim to review the recent progress in diagnosis and treatment of EBV-associated HS. Key words: Epstein-Barr virus; Hemophagocytic lymphohistiocytosis; Diagnosis; Treatment
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