Abstract

Chirality is a common phenomenon in nature. Designing and synthesis of novel artificial receptors to emulate the molecular recognition in living organism has become the challenging forefront of bioorganic chemistry and supramolecular chemistry. Molecular tweezers have been widely applied in chiral molecular recognition and detection for its easily modified structure. Molecular tweezers and their chiral recognition properties detected by spectrometry, chromatography and mass spec- trometry are summarized in this paper, and the prospect of molecular tweezers is also discussed. Keywords molecular tweezers artificial receptor; chiral recognition; spectrometry; chromatography; mass spectrometry

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