Abstract

As important intermediates for the development of biologically active molecules and fragrance etc., chiral secon- dary alcohols are synthesized through asymmetric hydrogenation. Recently, the asymmetric hydrosilylation process has been attracted because of its mild reaction conditions as well as inexpensive and safer reagent system. In this paper, some informa- tion about the recent development of the catalysts of the non-precious metal (Zn, Cu and so on) for asymmetric hydrosilylation reaction of prochiral ketones is briefly reviewed. Keywords asymmetric hydrosilylation; non-precious metal catalyst; chiral alcohol; prochiral ketone; progress

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