Abstract
AbstractHuman platelet antigens (HPAs) and their respective antibodies are responsible for different clinical conditions of alloimmune‐mediated thrombocytopenia. More recently, the involvement of HPA antibodies in rejection reactions to transplantation has been suggested. The detection of the causative HPA antibodies is therefore essential for the diagnosis and the implementation of preventive and therapeutic strategies. However, none of the available methods alone is presently able to detect all clinically relevant antibodies. In this review, we describe the old and new methods available for the detection of HPA antibodies, and discuss on their advantages and disadvantages.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
