Abstract
Tam metamorfoz geciren ipek boceklerinde, larval-pupal gelisim sirasinda sindirim kanali programlanmis hucre olumu yoluyla dejenere olmaktadir. Gelisim biyolojisinde programlanmis hucre olumu anahtar rol oynamaktadir. Programlanmis hucre olumu genel olarak, Apoptotik ve otofajik hucre olumu olarak isimlendirilen iki ana mekanizma ile gerceklesmektedir. Bu calismadaki amacimiz, larvalpupal metamorfoz sirasinda, Bombyx mori sindirim sisteminde meydana gelen metamorfik olaylarin gosterilmesidir. Histolojik teknikler kullanilarak morfolojik degisimler gosterilmistir; HE bulgularimiz, sindirim kanalinda meydana gelen olumde apoptoz ve otofajinin birlikte rol oynadigini gostermistir
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