Abstract
Prognostic Value of White Blood Cell Count, C-reactive protein, and Pentraxin-3 Levels in Patients with Acute Paraquat Poisoning
Highlights
Paraquat (N,N′-dimethyl-4,4′-bipyridinium dichloride) is an organic compound that is widely used as a herbicide
C-reactive protein, and pentraxin-3 levels at different time points As compared to the survival group, the non-survival group was associated with significantly higher white blood cell (WBC) count, C-reactive protein, and pentraxin-3 levels at day 0, 1, 2, and 3
The only exception pertained to the WBC count at day 3, which did not significantly differ between the two groups (Figure 1)
Summary
Paraquat (N,N′-dimethyl-4,4′-bipyridinium dichloride) is an organic compound that is widely used as a herbicide. Though paraquat poisoning occurs less frequently when compared to organophosphate poisoning, studies have demonstrated paraquat poisoning to be the leading cause of death due to herbicide poisoning, in both the developing and developed countries [1,2]. Paraquat poisoning can occur after skin exposure or inhalation, accidental or deliberate oral ingestion is known to be the commonest route. Paraquat poisoning may result in renal insufficiency, respiratory distress, hemodynamic instability, hepatic failure, and central nervous systemic disorders [3]. The diagnosis of paraquat poisoning is usually based on the history of paraquat exposure. Most diagnostic studies are focused on the evaluation of organ function [5]
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