Abstract

Introduction: Cell death markers, caspase-cleaved [CK-18 (M30)] and total cytokeratin [CK-18 (M65)] indicate the extent and relative proportions of apoptotic and necrotic cell death in acute liver failure (ALF) patients. Serum levels of apoptotic biomarkers [CK 18 (M30 and M 65)] are expected to be elevated in ALF compared to controls and these biomarkers may be linked to outcome.

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