Prognostic value of optic nerve sheath thickness in patients with central and peripheral vertigo

Abstract

Aim: To evaluate the role of the diameter of the optic nerve sheath (ONSD) in the differential diagnosis of the central and peripheral vertigo in patients, who had applied with the complaints of vertigo. Method: Our study had a prospective design and 113 vertigo patients were included in the study. The demographic characteristics, vital signs, symptoms accompanying vertigo and findings of the imaging examinations were evaluated. Results: The median age of our patients was 43 years (IQR: 17) and 44.2 % of them were males. 19.5 % of the patients were diagnosed with central and 80.5 % with peripheral vertigo. In our study, the median ONSD was 4.88 mm (IQR=0.86) in patients with central vertigo and 4.65 mm (IQR=0.20) in patients with peripheral vertigo. The median value of ONSD in patients with central vertigo was significantly higher (p=0.030). In our study, the area under the curve was 0.654 (95 % CI=0.498-0.810) and the sensitivity and specificity for the cut-off value of 4.65 mm were 68.2 % and 61.5 % respectively. Conclusion: We determined that ONSD was larger in patients with central vertigo. Further studies with larger subject size are needed on this topic.