Abstract
Background JDM is the most common idiopathic inflammatory myopathy in children. The Wedderburn scoring system is used to assess JDM muscle biopsies and categorizes muscle involvement into 4 domains: inflammatory, vascular, muscle fiber and connective tissue fibrosis (maximum scores: 12, 3, 10, and 2, respectively) and a 10-cm VAS measuring overall abnormality. A 10 cm VAS for chronicity (endomysial fibrosis, capillary loss and central nuclei) was also measured.
Highlights
Juvenile Dermatomyositis (JDM) is the most common idiopathic inflammatory myopathy in children
From 2011 Pediatric Rheumatology Symposium sponsored by the American College of Rheumatology Miami, FL, USA. 2-5 June 2011
A 10 cm VAS for chronicity was measured. In this retrospective cohort study JDM patients diagnosed from 1995-2008 underwent pre-treatment muscle biopsy guided by soft tissue MRI at CCHMC
Summary
From 2011 Pediatric Rheumatology Symposium sponsored by the American College of Rheumatology Miami, FL, USA. 2-5 June 2011. From 2011 Pediatric Rheumatology Symposium sponsored by the American College of Rheumatology Miami, FL, USA. Purpose Evaluate pre-treatment muscle biopsies of patient’s with probable or definite Juvenile Dermatomyositis (JDM) using the Wedderburn score to predict clinical outcomes
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