Prognostic Value of Bicycle Ergometry in Medically Treated Patients with Three-vessel Coronary Artery Disease

Abstract

“Patients with three-vessel coronary artery disease and stable angina assigned to coronary bypass surgery had an improved survival in the European Coronary Surgery Study. 1 European Coronary Surgery Study Croup Long term results of prospective randomized study of coronary artery bypass surgery in stable angina pectoris. Lancet. 1982; 2: 1173-1180 Google Scholar In the Coronary Artery Surgery Study 2 Passamani E Davies KB Gillespie MJ Killip T CASS Principal Investigators and their Associates Coronary Artery Surgery Study (CASS): a randomized trial of coronary artery bypass surgery: survival of patients with a low ejection fraction. N Engl J Med. 1985; 312: 1665-1671 Crossref PubMed Scopus (499) Google Scholar and in the Veterans Administration Cooperative Study, 3 Takaro T Hultgren HN Detre KM Peduzi P The Veterans Administration Cooperative Study of stable angina: current status. Circulation. 1982; 65: 60-67 Crossref PubMed Google Scholar improved survival in the surgical group was confirmed only in patients with three-vessel disease accompanied by impaired left ventricular function. Exercise testing has had prognostic significance in other studies, and the objective evidence of ischemia during exercise identifies a subgroup of patients with three-vessel disease at increased risk of dying during medical therapy. 4 McNeer JF Margolis JR Lee KL Kisslo JA Peter RH Kong Y et al. The role of the exercise test in the evaluation of patients for ischemic heart disease. Circulation. 1978; 57: 64-70 Crossref PubMed Scopus (383) Google Scholar , 5 Weiner DA Ryan TJ McCabe CH Chaitman BR Sheffield T Fisher LD et al. The role of exercise testing in identifying patients with improved survival after coronary bypass surgery. J Am Coll Cardiol. 1986; 8: 741-748 Abstract Full Text PDF PubMed Scopus (110) Google Scholar , 6 Bonow RO Kent KM Rosing DR Cordon Lan KK Lakatos E Borer JS et al. Exercise-induced ischemia in mildly symptomatic patients with coronary artery disease and preserved left ventricular function. N Engl J Med. 1984; 311: 1339-1345 Crossref PubMed Scopus (175) Google Scholar “Patients with three-vessel coronary artery disease and stable angina assigned to coronary bypass surgery had an improved survival in the European Coronary Surgery Study. 1 European Coronary Surgery Study Croup Long term results of prospective randomized study of coronary artery bypass surgery in stable angina pectoris. Lancet. 1982; 2: 1173-1180 Google Scholar In the Coronary Artery Surgery Study 2 Passamani E Davies KB Gillespie MJ Killip T CASS Principal Investigators and their Associates Coronary Artery Surgery Study (CASS): a randomized trial of coronary artery bypass surgery: survival of patients with a low ejection fraction. N Engl J Med. 1985; 312: 1665-1671 Crossref PubMed Scopus (499) Google Scholar and in the Veterans Administration Cooperative Study, 3 Takaro T Hultgren HN Detre KM Peduzi P The Veterans Administration Cooperative Study of stable angina: current status. Circulation. 1982; 65: 60-67 Crossref PubMed Google Scholar improved survival in the surgical group was confirmed only in patients with three-vessel disease accompanied by impaired left ventricular function. Exercise testing has had prognostic significance in other studies, and the objective evidence of ischemia during exercise identifies a subgroup of patients with three-vessel disease at increased risk of dying during medical therapy. 4 McNeer JF Margolis JR Lee KL Kisslo JA Peter RH Kong Y et al. The role of the exercise test in the evaluation of patients for ischemic heart disease. Circulation. 1978; 57: 64-70 Crossref PubMed Scopus (383) Google Scholar , 5 Weiner DA Ryan TJ McCabe CH Chaitman BR Sheffield T Fisher LD et al. The role of exercise testing in identifying patients with improved survival after coronary bypass surgery. J Am Coll Cardiol. 1986; 8: 741-748 Abstract Full Text PDF PubMed Scopus (110) Google Scholar , 6 Bonow RO Kent KM Rosing DR Cordon Lan KK Lakatos E Borer JS et al. Exercise-induced ischemia in mildly symptomatic patients with coronary artery disease and preserved left ventricular function. N Engl J Med. 1984; 311: 1339-1345 Crossref PubMed Scopus (175) Google Scholar