Abstract
A hypointense core of infarcted myocardium in T2-weighted CMR has been used as a noninvasive marker for intramyocardial hemorrhage and was related with adverse remodelling in recently published clinical trials. However, the clinical significance of such findings is not yet established.
Highlights
A hypointense core of infarcted myocardium in T2-weighted cardiovascular MR (CMR) has been used as a noninvasive marker for intramyocardial hemorrhage and was related with adverse remodelling in recently published clinical trials
In a multivariable regression model adjusted for significant variables in univariable regression analysis, the extent of late microvascular obstruction (MO) (p
When using a 3-level categorical variable including 1) MO and hypointense core both present 2) MO only present; 3) No MO and no hypointense core present, a risk gradient across the 3 groups could be observed (16.4% versus 10.8% versus 3.6%, p=0.002; Figure 1)
Summary
A hypointense core of infarcted myocardium in T2-weighted CMR has been used as a noninvasive marker for intramyocardial hemorrhage and was related with adverse remodelling in recently published clinical trials. The clinical significance of such findings is not yet established. Purpose Aim of this study was to evaluate determinants and prognostic impact of a hypointense infarct core in T2weighted cardiovascular MR (CMR) images, studied in patients after acute, reperfused ST-elevation myocardial infarction (STEMI)
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