Prognostic utility and clinical impact of adenosine stress perfusion CMR scan in patients with known coronary disease

Abstract

Results Mean age was 62 ± 12 years, and 24% were female. 19 patients had a history of previous coronary artery bypass grafting. A stress perfusion defect in viable myocardium was identified in 71 patients (71%). Of these, 52 (73%) subsequently underwent revascularization by either PCI (n = 49) or CABG (n = 3). Revascularisation was either unsuccessful or not performed in 19 patients (27%) due to the absence of significant symptoms, presence of mild perfusion abnormality or poor revascularisation targets. Among the 29 patients in whom no inducible perfusion defects were identified, revascularization was performed in 3 patients (1%) either due to ongoing symptoms (n = 2) or presence of significant luminal area reduction on intravascular ultrasound (IVUS) (n = 1). Follow-up data was available in 93 patients (93%). During a mean follow-up of 10.2 months, no adverse events were observed in patients without inducible perfusion defects on stress perfusion CMR. Among those patients with inducible perfusion defects on CMR who were treated initially with PCI, one patient died during follow-up and four patients were referred for surgical revascularisation due to significant disease progression/restenosis post PCI.