Abstract
Introduction: Pyogenic liver abscess (PLA) is a disease with formation of inflammatory isle in the liver parenchima with cavity with purulent collection. Aim The purpose of this study is to analyze the lethal cases in patients with PLA and create a prognostic index , which could provide the final outcome of treatment. Materials and methods: In our study we included 89 cases of PLA. We performed retro - prospective study in the period 2004-2009- we had 51 patients, and a prospective part - the period 2010-2017 with proven 38 patients. Results: We have 6 fatal cases - overall mortality rate of 7.6 %. Based on the SOFA Score (Septic Organ Failure Assessment score) we try to predict lethality in patients with PLA. After analyzing the lethal cases, we found that in 5 of 6 cases have a high SOFA score total> 10 points. Regarding the aim to create a prognostic index to assess the severity of the disease and treatment outcome "we used cross- tabulations and chi-square to match SOFA index and any of the following values: I value “ Immune deficiency”, II-Risk pathogenesis of abscess, III- Positive blood culture. Conclusion: The evaluation of the "critical point ” showed that the index > 9.5 sensitivity 80% and specificity was 87% ( 1-0129 = 87.1% ) Keywords pyogenic liver abscess, lethality, SOFA score.
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