Abstract
BackgroundThis retrospective study aimed to investigate the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and albumin for 30-day mortality in patients with postoperative acute pulmonary embolism (PAPE).MethodsWe retrospectively reviewed the medical records of 101 patients with PAPE admitted from September 1, 2012, to March 31, 2019. The characteristics, surgical information, admission examination data and mortality within 30 days after PAPE were obtained from our electronic medical recording system and follow-up. The associations between the NLR, PLR, and other predictors and 30-day mortality were analyzed with univariate and multivariate analyses. Then, the nomogram including the independent predictors was established and evaluated.ResultsTwenty-four patients died within 30 days, corresponding to a 30-day mortality rate of 23.8%. The results of the multivariate analysis indicated that both the NLR and albumin were independent predictors for 30-day mortality in patients with PAPE. The probability of death increased by approximately 17.1% (OR = 1.171, 95% CI: 1.073–1.277, P = 0.000) with a one-unit increase in the NLR, and the probability of death decreased by approximately 15.4% (OR = 0.846, 95% CI: 0.762c–0.939, P = 0.002) with a one-unit increase in albumin. The area under the curve of the nomogram was 0.888 (95% CI: 0.812–0.964).ConclusionOur findings showed that an elevated NLR and decreased albumin were related to poor prognosis in patients with PAPE. The NLR and albumin were independent prognostic factors for PAPE.
Highlights
This retrospective study aimed to investigate the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and albumin for 30-day mortality in patients with postoperative acute pulmonary embolism (PAPE)
Many researchers have reported that some predictors based on inflammation are associated with prognosis in patients with pulmonary embolism, such as the neutrophil-to-lymphocyte ratio (NLR), monocyte-tolymphocyte ratio (MLR), red blood cell distribution width (RDW), and C-reactive protein (CRP) [11,12,13,14]
Prognostic factors of PAPE Twenty-four patients died within 30 days, corresponding to a 30-day mortality rate of 23.8%
Summary
This retrospective study aimed to investigate the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and albumin for 30-day mortality in patients with postoperative acute pulmonary embolism (PAPE). Many researchers have reported that some predictors based on inflammation are associated with prognosis in patients with pulmonary embolism, such as the neutrophil-to-lymphocyte ratio (NLR), monocyte-tolymphocyte ratio (MLR), red blood cell distribution width (RDW), and C-reactive protein (CRP) [11,12,13,14]. Plasma albumin is one of the important indicators reflecting systemic nutritional status and is associated with prognosis in patients with acute pulmonary embolism [16]. This study was performed to investigate the relationship of admission NLR, plasma albumin and other predictors with 30-day mortality in patients with PAPE
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
